Pesquisa | Secretaria de Estado da Saúde

1.

Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system.

De Giovanni, Marco; Dang, Eric V; Chen, Kevin Y; An, Jinping; Madhani, Hiten D; Cyster, Jason G.

Immunity ; 56(7): 1548-1560.e5, 2023 07 11.

Artigo Inglês | MEDLINE | ID: mdl-37279752

2.

Fooling TLR4 to promote fungal virulence.

León, Beatriz.

Immunity ; 55(9): 1591-1593, 2022 09 13.

Artigo Inglês | MEDLINE | ID: mdl-36103858

3.

Secreted fungal virulence effector triggers allergic inflammation via TLR4.

Dang, Eric V; Lei, Susan; Radkov, Atanas; Volk, Regan F; Zaro, Balyn W; Madhani, Hiten D.

Nature ; 608(7921): 161-167, 2022 08.

Artigo Inglês | MEDLINE | ID: mdl-35896747

4.

CryptoCEN: A Co-Expression Network for Cryptococcus neoformans reveals novel proteins involved in DNA damage repair.

O'Meara, Matthew J; Rapala, Jackson R; Nichols, Connie B; Alexandre, A Christina; Billmyre, R Blake; Steenwyk, Jacob L; Alspaugh, J Andrew; O'Meara, Teresa R.

PLoS Genet ; 20(2): e1011158, 2024 Feb.

Artigo Inglês | MEDLINE | ID: mdl-38359090

5.

The structure of a C. neoformans polysaccharide motif recognized by protective antibodies: A combined NMR and MD study.

Hargett, Audra A; Azurmendi, Hugo F; Crawford, Conor J; Wear, Maggie P; Oscarson, Stefan; Casadevall, Arturo; Freedberg, Darón I.

Proc Natl Acad Sci U S A ; 121(7): e2315733121, 2024 Feb 13.

Artigo Inglês | MEDLINE | ID: mdl-38330012

6.

Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans.

Gusa, Asiya; Yadav, Vikas; Roth, Cullen; Williams, Jonathan D; Shouse, Eva Mei; Magwene, Paul; Heitman, Joseph; Jinks-Robertson, Sue.

Proc Natl Acad Sci U S A ; 120(4): e2209831120, 2023 Jan 24.

Artigo Inglês | MEDLINE | ID: mdl-36669112

7.

Similar evolutionary trajectories in an environmental Cryptococcus neoformans isolate after human and murine infection.

Sephton-Clark, Poppy; McConnell, Scott A; Grossman, Nina; Baker, Rosanna P; Dragotakes, Quigly; Fan, Yunfan; Fu, Man Shun; Gerbig, Gracen; Greengo, Seth; Hardwick, J Marie; Kulkarni, Madhura; Levitz, Stuart M; Nosanchuk, Joshua D; Shoham, Shmuel; Smith, Daniel F Q; Stempinski, Piotr; Timp, Winston; Wear, Maggie P; Cuomo, Christina A; Casadevall, Arturo.

Proc Natl Acad Sci U S A ; 120(2): e2217111120, 2023 01 10.

Artigo Inglês | MEDLINE | ID: mdl-36603033

8.

Amoeba predation of Cryptococcus: A quantitative and population genomic evaluation of the accidental pathogen hypothesis.

Sauters, Thomas J C; Roth, Cullen; Murray, Debra; Sun, Sheng; Floyd Averette, Anna; Onyishi, Chinaemerem U; May, Robin C; Heitman, Joseph; Magwene, Paul M.

PLoS Pathog ; 19(11): e1011763, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37956179

9.

Kicking sleepers out of bed: Macrophages promote reactivation of dormant Cryptococcus neoformans by extracellular vesicle release and non-lytic exocytosis.

de Castro, Raffael Júnio Araújo; Marina, Clara Luna; Sturny-Leclère, Aude; Hoffmann, Christian; Bürgel, Pedro Henrique; Wong, Sarah Sze Wah; Aimanianda, Vishukumar; Varet, Hugo; Agrawal, Ruchi; Bocca, Anamélia Lorenzetti; Alanio, Alexandre.

PLoS Pathog ; 19(11): e1011841, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-38033163

10.

Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents.

Lee, Hiu Ham; Carmichael, Dylan J; Ríbeiro, Victoria; Parisi, Dana N; Munzen, Melissa E; Charles-Niño, Claudia L; Hamed, Mohamed F; Kaur, Ettiman; Mishra, Ayush; Patel, Jiya; Rooklin, Rikki B; Sher, Amina; Carrillo-Sepulveda, Maria A; Eugenin, Eliseo A; Dores, Michael R; Martinez, Luis R.

PLoS Pathog ; 19(4): e1010941, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-37115795

11.

A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformans.

Probst, Corinna; Hallas-Møller, Magnus; Ipsen, Johan Ø; Brooks, Jacob T; Andersen, Karsten; Haon, Mireille; Berrin, Jean-Guy; Martens, Helle J; Nichols, Connie B; Johansen, Katja S; Alspaugh, J Andrew.

PLoS Pathog ; 19(4): e1010946, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-37099613

12.

The hybrid RAVE complex plays V-ATPase-dependent and -independent pathobiological roles in Cryptococcus neoformans.

Choi, Jin-Tae; Choi, Yeseul; Lee, Yujin; Lee, Seung-Heon; Kang, Seun; Lee, Kyung-Tae; Bahn, Yong-Sun.

PLoS Pathog ; 19(10): e1011721, 2023 10.

Artigo Inglês | MEDLINE | ID: mdl-37812645

13.

Arginase 1 Expression by Macrophages Promotes Cryptococcus neoformans Proliferation and Invasion into Brain Microvascular Endothelial Cells.

Hansakon, Adithap; Ngamphiw, Chumpol; Tongsima, Sissades; Angkasekwinai, Pornpimon.

J Immunol ; 210(4): 408-419, 2023 02 15.

Artigo Inglês | MEDLINE | ID: mdl-36548474

14.

Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen.

Sun, Sheng; Roth, Cullen; Floyd Averette, Anna; Magwene, Paul M; Heitman, Joseph.

Proc Natl Acad Sci U S A ; 119(8)2022 02 22.

Artigo Inglês | MEDLINE | ID: mdl-35169080

15.

Description of Cryptococcosis Following SARS-CoV-2 Infection: A Disease Survey Through the Mycosis Study Group Education and Research Consortium (MSG-19).

Walker, Jeremey; McCarty, Todd; McGwin, Gerald; Ordaya, Eloy E; Vergidis, Paschalis; Ostrosky-Zeichner, Luis; Mammadova, Mehriban; Spec, Andrej; Rauseo, Adriana M; Perfect, John; Messina, Julia; Vilchez, Gabriel; McMullen, Rachel; Jones, Carolynn T; Pappas, Peter G.

Clin Infect Dis ; 78(2): 371-377, 2024 Feb 17.

Artigo Inglês | MEDLINE | ID: mdl-37713207

16.

Dectin-3-targeted antifungal liposomes efficiently bind and kill diverse fungal pathogens.

Choudhury, Quanita J; Ambati, Suresh; Link, Collin D; Lin, Xiaorong; Lewis, Zachary A; Meagher, Richard B.

Mol Microbiol ; 120(5): 723-739, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37800599

17.

Multi-locus sequence typing and phylogenetics of Cryptococcus neoformans AD hybrids.

Cogliati, M; Chidebelu, P E; Hitchcock, M; Chen, M; Rickerts, V; Ackermann, S; Desnos Ollivier, M; Inácio, J; Nawrot, U; Florek, M; Kwon-Chung, K J; Yang, D-H; Firacative, C; Puime, C A; Escandon, P; Bertout, S; Roger, F; Xu, J.

Fungal Genet Biol ; 170: 103861, 2024 Feb.

Artigo Inglês | MEDLINE | ID: mdl-38128716

18.

Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection.

Gibson, Josie F; Bojarczuk, Aleksandra; Evans, Robert J; Kamuyango, Alfred Alinafe; Hotham, Richard; Lagendijk, Anne K; Hogan, Benjamin M; Ingham, Philip W; Renshaw, Stephen A; Johnston, Simon A.

PLoS Pathog ; 18(4): e1010389, 2022 04.

Artigo Inglês | MEDLINE | ID: mdl-35446924

19.

Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape mechanisms.

Dragotakes, Quigly; Jacobs, Ella; Ramirez, Lia Sanchez; Yoon, Olivia Insun; Perez-Stable, Caitlin; Eden, Hope; Pagnotta, Jenlu; Vij, Raghav; Bergman, Aviv; D'Alessio, Franco; Casadevall, Arturo.

PLoS Pathog ; 18(7): e1010697, 2022 07.

Artigo Inglês | MEDLINE | ID: mdl-35816543

20.

On the relationship between Pathogenic Potential and Infective Inoculum.

Smith, Daniel F Q; Casadevall, Arturo.

PLoS Pathog ; 18(6): e1010484, 2022 06.

Artigo Inglês | MEDLINE | ID: mdl-35696437

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